UPDATE: Semi truck at Hwy 22 and Thrifty Car Rental has been cleared. Traffic beginning to move in both directions. 
UPDATE 01/02/2015 5:05pm - Per Teton County Sheriff's Office Dispatch, semi truck has been cleared from Highway 22 near Thrifty Car Rental. Both eastbound and westbound traffic are flowing again and congestion is beginning to ease.
ORIGINAL MESSAGE 01/02/2015 4:25pm - Per Teton County Sheriff's Office Dispatch, there is a semi truck blocking all lanes of travel on Highway 22 near Thrifty Car Rental (near the "Y" intersection). Wyoming Highway Patrol is on scene trying to clear the blockage, but at this time traffic is stopped in both directions. Unknown when blockage will be cleared. We will send an update Nixle when highway is reopened. Avoid area for the time being if possible.
Address/Location
Teton County Emergency Management
3240 Adams Canyon Dr
Jackson, WY 83001
Contact
Emergency: 9-1-1
Non-emergencies: 307-733-9572